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  • Category: Nanotechnology
  • Founded: Aug 16, 2003
  • Language: English
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#5111 From: misscraps@...
Date: Wed Apr 11, 2012 9:08 pm
Subject: next Science Fiction book club meeting
misscraps
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If anyone would like to join us, the next SF club meeting (SNAFFU) will be April 14 at 2 p.m. at the Barnes and Noble bookstore on Maryland Parkway (about 1 block from Flamingo).  Afterwards we sometimes go to a nearby deli for food.

#5112 From: "Shawn Jipp" <sjipp@...>
Date: Tue Apr 17, 2012 6:31 am
Subject: Wearable Computing in our future!
sjipp
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#5113 From: Shawn Jipp <sjipp@...>
Date: Tue Apr 17, 2012 3:30 pm
Subject: Einstein Quotes
sjipp
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Albert Einstein Quotes

This quote contains photos.

"I want to know [God's] thoughts, the rest are details."

Albert Einstein

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"A Talk with Einstein," The Listener 54, (1955) pg. 370-371

In Einstein's quest to understand the Creator's rules for the universe, he frequently spoke on discovering the underlying principles of reality.

846

This quote contains photos.

"Any man who reads too much and uses his own brain too little falls into lazy habits of thinking"

Albert Einstein

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A Close Look at the World's Greatest Thinker, American Magazine, (June 1930)

Einstein was interviewed by M. K. Wisehart for American magazine, and spoke the above quote, which continues, "just as the man who spends too much time in the theaters is apt to be content with living vicariously instead of living his own life.

This quote contains photos.

"Try not to become a man of success, but rather try to become a man of value."

Albert Einstein

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German Physicist inspirationalMotivational Quote of the Day

Albert Einstein

756
756

"The only mistake in life is the lesson not learned."

Albert Einstein

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Learning Life Quote of the Day

Albert Einstein

750
750

"Learn from yesterday, live for today, hope for tomorrow."

Albert Einstein

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Editor's Pick Einstein Hope LearningLife Quote of the Day

Albert Einstein

756
756

"The only thing that interferes with my learning is my education."

Albert Einstein

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Funny German Physicist Quote of the Day Short

Featured Book: The Most Brilliant Thoughts of All Time (In Two Lines or Less) by John M. Shanahan

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You don't have to be a genius to sound like one. Here's a collection of the most profound and provocative wit and wisdom in the English language in two lines or less. Edited by entrepreneur John M. Shanahan, who created the wildly successful Hooked on Phonics program, this wonderful book presents the best that has been thought and said on every imaginable topic.

 

Albert Einstein

738
738

"Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world."

Albert Einstein

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Art German Physicist

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Albert Einstein

741
741

"It's not that I'm so smart, it's just that I stay with problems longer."

Albert Einstein

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German Physicist Motivational Quote of the Day

Albert Einstein

737
737

"Out of clutter, find Simplicity. From discord, find Harmony. In the middle of difficulty lies Opportunity."

Albert Einstein

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Editor's Pick inspirational MotivationalQuote of the Day Success

Albert Einstein

755
755

"You ask me if I keep a notebook to record my great ideas. I've only ever had one."

Albert Einstein

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Editor's Pick Funny German PhysicistQuote of the Day

Albert Einstein

714
714

"There are only two ways to live your life. One is as though nothing is a miracle. The other is as though everything is a miracle."

Albert Einstein

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inspirational Life Miracles

Albert Einstein

755
755

"Not everything that can be counted counts, and not everything that counts can be counted."

Albert Einstein

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German Physicist Motivational Quote of the Day

Albert Einstein

755
755

"We act as though comfort and luxury were the chief requirements of life, when all that we need to make us happy is something to be enthusiastic about."

Albert Einstein

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Editor's Pick Happiness inspirationalLife Quote of the Day

Albert Einstein

667
667

"As far as the laws of mathematics refer to reality, they are not certain; and as far as they are certain, they do not refer to reality."

Albert Einstein

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Funny Quote of the Day Short

Albert Einstein

666
666

"Great spirits have always encountered violent opposition from mediocre minds."

Albert Einstein

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Einstein German Physicist MotivationalQuote of the Day

 

Albert Einstein

648
648

"If A equals success, then the formula is A equals X plus Y and Z, with X being work, Y play, and Z keeping your mouth shut."

Albert Einstein

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Motivational Quote of the Day Success

Albert Einstein

652
652

"If most of us are ashamed of shabby clothes and shoddy furniture, let us be more ashamed of shabby ideas and shoddy philosophies... It would be a sad situation if the wrapper were better than the meat wrapped inside it."

Albert Einstein

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Appearance Editor's Pick Ideas LifePhilosophy Quote of the Day

Albert Einstein

641
641

"The man who regards his own life and that of his fellow creatures as meaningless is not merely unfortunate but almost disqualified for life."

Albert Einstein

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Humankind Life Meaning Of LifeQuote of the Day

Albert Einstein

638
638

"A person starts to live when he can live outside himself."

Albert Einstein

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Editor's Pick Einstein Life Quote of the Day

Albert Einstein

614
614

"It is every man's obligation to put back into the world at least the equivalent of what he takes out of it."

Albert Einstein

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Editor's Pick Humankind Life Meaning Of Life Quote of the Day

Albert Einstein

575
575

This quote contains photos.

"You can't blame gravity for falling in love."

Albert Einstein

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Cute Love

Featured Book: The Most Brilliant Thoughts of All Time (In Two Lines or Less) by John M. Shanahan

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You don't have to be a genius to sound like one. Here's a collection of the most profound and provocative wit and wisdom in the English language in two lines or less. Edited by entrepreneur John M. Shanahan, who created the wildly successful Hooked on Phonics program, this wonderful book presents the best that has been thought and said on every imaginable topic.

 

Albert Einstein

581
581

"Common sense is the collection of prejudices acquired by age eighteen."

Albert Einstein

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Albert Einstein

703
703

"Wisdom is not a product of schooling but of the lifelong attempt to acquire it"

Albert Einstein

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Albert Einstein

528
528

"The value of achievement lies in the achieving."

Albert Einstein

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Achievement inspirationalMotivational Quote of the Day

Albert Einstein

755
755

"Memory is deceptive because it is colored by today's events."

Albert Einstein

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Color German Physicist

Albert Einstein

523
523

"We can't solve problems by using the same kind of thinking we used when we created them."

Albert Einstein

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Attitude German Physicist

Albert Einstein

423
423

"Any man who can drive safely while kissing a pretty girl is simply not giving the kiss the attention it deserves."

Albert Einstein

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Cute German Physicist

Albert Einstein

530
530

"(Bias against the Negro) is the worst disease from which the society of our nation suffers"

Albert Einstein

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Albert Einstein

463
463

"The world is a dangerous place. Not because of the people who are evil; but because of the people who don't do anything about it."

Albert Einstein

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Action Complacency Evil People

Albert Einstein

422
422

"Education is what remains after one has forgotten everything he learned in school."

Albert Einstein

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Education School

Albert Einstein

420
420

"The true sign of intelligence is not knowledge but imagination."

Albert Einstein

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Art German Physicist

Albert Einstein

394
394

"Joy in looking and comprehending is nature's most beautiful gift."

Albert Einstein

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Awareness German Physicist

Albert Einstein

387
387

"You have to learn the rules of the game. And then you have to play better than anyone else."

Albert Einstein

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Achievement American PoliticianGerman Physicist

Albert Einstein

755
755

"Women marry men hoping they will change. Men marry women hoping they will not. So each is inevitably disappointed."

Albert Einstein

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Marriage Men Men And WomenWomen

Albert Einstein

361
361

"Nature hides her secrets because of her essential loftiness, but not by means of ruse."

Albert Einstein

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Albert Einstein

349
349

"Strange is our Situation Here Upon Earth."

Albert Einstein

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Einstein

Featured Book: The Most Brilliant Thoughts of All Time (In Two Lines or Less) by John M. Shanahan

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You don't have to be a genius to sound like one. Here's a collection of the most profound and provocative wit and wisdom in the English language in two lines or less. Edited by entrepreneur John M. Shanahan, who created the wildly successful Hooked on Phonics program, this wonderful book presents the best that has been thought and said on every imaginable topic.

 

Albert Einstein

329
329

"Few people are capable of expressing with equanimity opinions which differ from the prejudices of their social environment"

Albert Einstein

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Albert Einstein

354
354

"My life is a simple thing that would interest no one. It is a known fact that I was born and that is all that is necessary."

Albert Einstein

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Birth Einstein

Albert Einstein

313
313

"How I wish that somewhere there existed an island for those who are wise and of good will"

Albert Einstein

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Albert Einstein

281
281

"A man's ethical behavior should be based effectually on sympathy, education, and social ties; no religious basis is necessary. Man would indeed be in a poor way if he had to be restrained by fear of punishment and hope of reward after death."

Albert Einstein

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Behavior

Albert Einstein

295
295

"Innovation is not the product of logical thought, although the result is tied to logical structure."

Albert Einstein

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Innovation

Albert Einstein

282
282

"The bitter and the sweet come from the outside, the hard from within, from one's own efforts."

Albert Einstein

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Albert Einstein

311
311

"In a healthy nation there is a kind of dramatic balance between the will of the people and the government, which prevents its degeneration into tyranny."

Albert Einstein

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Government

Albert Einstein

247
247

"Every kind of peaceful cooperation among men is primarily based on mutual trust and only secondarily on institutions such as courts of justice and police"

Albert Einstein

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Trust

Albert Einstein

250
250

"Out of the multitude of our sense experiences we take, mentally and arbitrarily, certain repeatedly occurring complexes of sense impression (partly in conjunction with sense impressions which are interpreted as signs for sense experiences of others), and we attribute to them a meaning the meaning of the bodily object."

Albert Einstein

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Experience

"You can never solve a problem on the level on which it was created."

Albert Einstein

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Create German Physicist

Albert Einstein

0
0

"I have never looked upon ease and happiness as ends in themselves - such an ethical basis I call more proper for a herd of swine. The ideals which have lighted me on my way and time after time given me new courage to face life cheerfully, have been Truth, Goodness, and Beauty."

Albert Einstein

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Beauty Integrity

Albert Einstein

0
0

"All our lauded technological progress -- our very civilization - is like the axe in the hand of the pathological criminal."

Albert Einstein

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Einstein

Albert Einstein

2
2

"Science can only ascertain what is, but not what should be, and outside of its domain value judgments of all kinds remain necessary."

Albert Einstein

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Judgement Science And Scientists

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Albert Einstein

1
1

"“I want to know how God created this world. I am not interested in this or that phenomenon, in the spectrum of this or that element. I want to know His thoughts; the rest are details."

Albert Einstein

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God

Albert Einstein

0
0

"“Nature hides her secrets because of her essential loftiness, but not by means of ruse."

Albert Einstein

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Nature

Featured Book: The Most Brilliant Thoughts of All Time (In Two Lines or Less) by John M. Shanahan

http://ws.assoc-amazon.com/widgets/q?_encoding=UTF8&Format=_SL160_&ASIN=0060194111&MarketPlace=US&ID=AsinImage&WS=1&tag=greatquotesco-20&ServiceVersion=20070822 http://www.assoc-amazon.com/e/ir?t=greatquotesco-20&l=as2&o=1&a=0060194111

You don't have to be a genius to sound like one. Here's a collection of the most profound and provocative wit and wisdom in the English language in two lines or less. Edited by entrepreneur John M. Shanahan, who created the wildly successful Hooked on Phonics program, this wonderful book presents the best that has been thought and said on every imaginable topic.

 

Albert Einstein

0
0

"A man's moral worth is not measured by what his religious beliefs are but rather by what emotional impulses he has received from Nature during his lifetime."

Albert Einstein

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Morality Nature Religion Religious

Albert Einstein

1
1

"It is best, it seems to me, to separate one's inner striving from one's trade as far as possible. It is not good when one's daily break is tied to God's special blessing."

Albert Einstein


#5114 From: Eric Anderson <eric25001@...>
Date: Tue Apr 17, 2012 6:31 pm
Subject: Fullerene C60 administration doubles rat lifespan with no toxicity
eric25001
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Wow.  Lets wait for this to be confirmed.  DOUBLES the life span is big.
That would mean for a human change from 80 years to 160 years.
Lets hope this works out! Eric from the SALT pits!
 
And what would this do for populations? The topic of Boulders next meeting!
 

Fullerene C60 administration doubles rat lifespan with no toxicity

Researchers at the University of Paris and colleagues fed the molecule fullerene (C60 or “buckyballs”) dissolved in olive oil to rats and found it almost doubles their lifespan, with no chronic toxicity.

The results suggest that the effect of C60, an antioxidant, on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress, according to the researchers.
Pharmacokinetic studies show that dissolved C60 is absorbed by the gastro-intestinal tract and eliminated in a few tens of hours.
“These results of importance in the fields of medicine and toxicology should open the way for the many possible biomedical applications of C60 including cancer therapy, neurodegenerative disorders, and aging,” the researcher suggest.
“C60 can be administered orally, and as it is now produced in tons, it is no longer necessary to resort to its water-soluble derivatives, which are difficult to purify and, in contrast to pristine C60, may be toxic.

Since 1993, countless studies showed that fullerene (C60) and derivatives exhibit paramount potentialities in several fields of biology and medicine, mainly including specific DNA cleavage, imaging, UV and radioprotection, antiviral, antioxidant, and anti-amyloid activities, allergic response and angiogenesis inhibitions, immune stimulating and antitumor effects, enhancing effect on neurite outgrowth, gene delivery, and even hair-growing activity, a summary in the Biomaterials paper stated.

Ref.: Baati T, et al., The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene, Biomaterials (2012), doi:10.1016/j.biomaterials.2012.03.036


#5115 From: "Shawn Jipp" <sjipp@...>
Date: Wed Apr 18, 2012 7:56 am
Subject: OLEDs in our FUTURE
sjipp
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OLEDs larger, brighter, better... from Philips

http://ast.hcsm1.com/images/pp/454/2011/pr105_1bbf1b8cd.jpg

The future will see fascinating applications making use of OLED technology: Furniture which emits light or window screens which let in the sunlight during day but emit the same natural light in the evening thanks to incorporated transparent OLEDs. Philips as leading company in industrialization and mass customization of this light technology will present at Light + Building the next steps in OLED lighting. At this point we do not want to spoil the surprise but it is fair to say: larger, brighter, better...

http://www.lighting.philips.com/main/connect/events/light_building/philips-lumiblade.wpd

 


#5116 From: "Futuretalk" <futuretalk@...>
Date: Thu Apr 19, 2012 1:11 pm
Subject: Las Vegas 2037
futuretalk2030
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Las Vegas 2037

By Dick Pelletier

The fictional Smith clan might well be the family of Las Vegas' future. And in 25 years, you too might cruise around in driverless cars, hop a scramjet to anywhere on Earth in an hour, be pampered by a robot servant, communicate at times using only your thoughts, and live in an ageless, forever-healthy body.

Now kick back, relax, and transcend yourself into the future. Enjoy this fun glimpse into the trials and tribulations of a typical "2037" family!

Las Vegas family of five and robot, 25 years into the future

5:30 A.M.

It is a beautiful winter morning in 2037. In this area of Las Vegas, just off Tropicana between Rainbow and Buffalo, about a third of the residents have already begun their day's activities. Many of the remaining households have not yet begun to stir.

Among the homes on this street is a large one-story Spanish revival-style house of the type that was frequently built in this area during the construction boom of the early 21st century. A streamlined cobalt-blue auto-drive car is parked in the driveway. The street is quiet.

6:00 A.M.

With barely a perceptible click, the Smith house turns itself on, as it has every morning since the family had it retrofitted with the Smart House System 10 years ago. Within seconds, warm air flows from the home's breathing ducts while the water heater checks to make sure there's plenty of hot water. In the kitchen, the newly-installed nano-replicator comes to life ready to create coffee, milk, organic fruit juices, and bio-friendly breakfast selections for each member of the family.

Walls in every room begin to dimly display, in soft tones, 3-D outdoor scenes with pleasant fresh air odors and appropriate sounds seashores, country lakes, and snow-capped mountain peaks. These personalized wall displays add a psychological touch that the Smiths have grown to enjoy.

6:30 A.M.

Stretching his arms in a human manner, Bradley the Smiths' life-like robot completes the energy renewal session of his power-pack. Bradley is a state-of-the-art 3rd generation robot capable of performing most household chores. He understands human moods and can participate in limited conversation. Recently Bradley has developed a stubborn, all-too-human personality, complaining that he is not given enough respect. The Smiths find this trait amusing they think the world of their robot.

While browsing the net, Bradley learned of the upcoming 4th generation robots. "4th-gens", as they are called, are expected to achieve greater-than-human intelligence, and Bradley has asked to be upgraded when they become available in about five years. But the Smiths say no. They fear more intelligence would change Bradley's personality, and they love him just the way he is.

An obedient Bradley heads for the master bedroom for his first task of the day. He gently knocks on the door, calling out the Smiths' names and the time in a pleasant, southern drawl: "Good morning, y'all it's time to rise and shine".

On the other side of the door, Alicia Smith, a 45-year-old medical information specialist, is out of bed in a flash. Pulling on some sweats, Alicia heads for the home gym, where electronic weights and other gadgets read instructions from her identity chip implant, and she begins her 20-minute workout.

The Smith children poke fun at their mother's exercising. Nearly ten years ago, gene therapies became available that made it unnecessary for people to exercise. Physical changes that exercise brought about are mimicked by just taking a pill but Alicia says she exercises because she enjoys the sweat and earthy feelings she gets from putting her body through a physical workout.

Meanwhile, her husband Randolph Smith, 50, a senior executive at a Las Vegas-based multinational corporation, is having a harder time. He's still feeling exhausted from the night before, when his 85-year-old widowed mother, Carlotta, who lives with the family, kept him up most of the night talking about prospective dates she met at an on-line virtual reality (VR) party.

Six weeks ago, Carlotta became the first in the Smith family to undergo complete genetic rejuvenation which transformed her 85-year-old body into a striking 20-something beauty. Alicia and Randolph underwent stem cell and genetic engineering therapies that keep their bodies in perfect health internally, but have so far opted against regenerating their outer skin. Randolph believes his "dignified" look helps influence co-workers at the job, and Alicia first wants to see how her mother-in-law handles the change from a grandmotherly to a teenage look.

Glancing in the mirror, Carlotta thinks, "wow is that really me?" I can hardly wait to find a great guy to begin sharing my life with again maybe a mature person who has undergone the same procedure" she muses. And she thinks her son should help her critique likely candidates.

After finally convincing his mother that she needs to make her own choices, Randolph, unable to fall asleep, spent a couple of hours at the powerful com-center in the study, talking with his counterparts in the firm's Tokyo office. But this morning, he can't afford to be late. With a grunt, he rolls out of bed and heads for the bathroom, where he swishes "Nano-rinse", a product that sends tiny nanoparticles scurrying around his teeth making them sparkling clean then hurries to get dressed. As he does, Carlotta appears on the wall-screen trying again to get his help.

Randolph silently thought-clicks the video-send image off so Carlotta can't see him in his boxer shorts, and then says in a curt voice, "Mom, I don't want to get involved; I'm late; I have to go". When Randolph heads for the kitchen, he leaves the bed unmade. Bradley always directs nanobot cleaning procedures that keep clothing and household items organized and like-new.

7:00 A.M.

Down the hall, 11-year-old Mike feels a gentle tugging on his sleeve. It's his dog, "Max", waking him up. Although Mike thinks of him as a real dog, Max is a robo-pet a small robot less sophisticated than Bradley that Mike has enjoyed ever since his real bull terrier ran away. Max helped Mike learn to read and now helps with his studies.

This morning, Mike asks his dog to retrieve Thought Police, his favorite group, from the house-com and make it available for him to listen on the way to school. Max, who barks, and also speaks perfect "human", says he'll do so but only if Mike promises to not pull any more tricks in class. Yesterday, he downloaded a program and sent it directly into his best friend Robbie's neurons, which made Robbie, believe they were at Disneyland. When Mike's teacher saw what happened, she came within an inch of sending Mike to virtual detention. Mike promised to not do that again.

Across the hall, Mike's sister, 15-year-old Sandy, awakens to the quiet and gentle voice of "Meggers", her own personal hologram. Meggers was created years ago as an avatar an on-screen image designed after Alicia's favorite movie star, Meg Ryan. In the beginning, Meggers helped family members interface with the house-com. But as technology advanced, avatars gained the ability to appear off screen as a life-like hologram. And thanks to recently-invented "nanobot swarm", Sandy can now actually feel Meggers when they hold hands or hug.

Sandy pleaded to keep Meggers as her room-mate and advisor, and the two have been together ever since. Sandy controls Meggers with only her thoughts, and Meggers, connected to the Internet, helps Sandy with her education. They have become an inseparable pair.

Sandy asks Meggers to download a movie Even though I'm a Granddaddy with a Cane, Awaiting Genetic Rejuvenation, I Still Know What You Did Last Summer. Her classmates say it's hilarious.

Meggers agrees to get the movie, and reminds Sandy that she must be in class by 8:00 A.M., so there's no time to waste.

7:15 A.M.

In the stark white kitchen, Alicia reads Bradley a list of chores she wants him to do today monitor the housekeeping `bots that polish floors, clean windows, and make beds. Bradley, who was programmed with a southern-style voice synthesizer because it reminded Randolph of his Tennessee roots, acknowledges her commands with a burst of "You ain't nothin' but a Houndog", and Alicia, turning away smiling, is satisfied.

When the Smiths paid $100,000 and brought the 6-foot-tall robot home two years ago, they were not sure they would ever adjust to having it around. In fact, it had taken several weeks and some near-catastrophes (such as the time Bradley ordered dog food from the replicator instead of oat bran, and served it to everyone with milk for breakfast). But they eventually learned to input specific information the robot needed to function properly. Now Bradley is an irreplaceable part of their lives.

7:30 A.M.

Randolph joins the family for breakfast, and observes that the replicator has created customized "nutraceutical" meals for each family member that meets their nutritional and medical needs for the day. Nutraceutical foods, which originated in 2000, but have only become widespread since 2020, use special proteins that deliver drugs to targeted areas of the body to prevent disease. Tiny nano-capsules analyze the body's health condition and create a nutritional and health profile custom-designed for each family member including their allergies, nutritional deficiencies, etc. Nutraceutical foods are also tailor made to excite each person's taste buds.

Mike and Sandy begin "inhaling their breakfast as usual, when their mom says, "slow down gang, we're not going to the races". Carlotta makes her entrance with shocking news. Bolstered with her new-found youthful figure and looks, she tells everyone she is off today to audition for a cheer leader position on Las Vegas' new entry to the NBA The Desert Stars.

Trillionair Saul Allendale formed the team around genetically-rejuvenated stars Kobe Bryant, LeBron James, Kareem Abdul Jabbar, Bill Russell, Magic Johnson, Michael Jordan, and Larry Bird. Las Vegas fans have gone wild supporting their new team. Playoff fever reigns throughout the state.

This is the first season, and Carlotta hopes to gain a cheer leader slot. Sandy approves with a hip "way to go gran", and Mike throws her a high five. But Randolph is having a problem with his mom's new-found youth trip he feels she is a little too outgoing and too trusting. He can't quite pin it down, but he feels an impending danger. Casting intuitions aside, he reasons she will be OK.

8:00 A.M

Randolph swallows a "fitness" pill that provides all the benefits of a morning workout, plus guards his light skin not yet protected with rejuvenative therapy against the sunlight burning through a thinning ozone layer. He kisses Alicia, grabs highlight printouts of the New York Times and Las Vegas Sun/Journal, and heads out the door. Then he has a thought "Alicia, honey; let's meet for lunch and give ourselves a treat. How about La Caf St Pierre? I can be there by 12:30". Alicia says, "great, I'll see you there".

In the driveway, Randolph approaches his pride and joy a brand new driverless Andromeda 5000. The car door, receiving security OK from a chip implanted in Randolph's skin, opens automatically and the black leather interior quickly adjusts to Randolph's 6-foot-1 frame. After the power seat, mirror and control panel moves into place, Randolph settles down and voices his destination to the onboard computer.

Coasting down Belshire, the Andromeda noses onto Tropicana automatically snaking in and out of traffic, and in just eight minutes, turns onto Eastern for the final mile to the company parking lot.

8:15 A.M.

Back home, Mike is talking with his computer pen pal in China, Bingbing Xu, asking questions for his social studies project on life in another country. When the driverless school van appears on the house wall-screens, Mike hurriedly signs off without even hearing her answer to whether kids in Beijing listen to future-rock too. He grabs his "smart card" a PC about the size of a 3x5 card, which carries his educational history and dashes out of the house.

The trip to school is a short one, since Mike attends The New Concepts School, a small neighborhood public school with only 300 students, nestled near Reno and Jones. Mike's school is part of a pilot program started by the Las Vegas Unified School District to scale down school size and return the informality of community. Thanks to Direct Mind Information Transfer, educational opportunities have been greatly expanded.

Mike and his classmates walk into the homeroom and sit at their workstations. Susan Michael, their youthful teacher, queries each station to see which students completed their homework. Mike is not among them. Susan tells the students it's time for a lesson in ancient cultures. As she pushes a button, the walls, ceiling, and floor of the classroom, all large-screen displays portray a scene from the ancient Mayan city of Tikal in Guatemala.

The students find themselves sitting inside a ceremonial plaza circa AD 550, surrounded by flat-top pyramids. When a student asks what Tikal looks like today, Susan hits a key and the computer displays photograph-quality images of the Mayan ruins, circa 2037. Mike takes advantage of the darkened room to torment arch-rival Robbie with a toy ultra-faser. It is quickly confiscated.

8:30 A.M.

On his way to the living room, Bradley tunes his powerful brain into the My Life Bits program to make sure each family member's daily activities are being recorded and stored properly. Recording every event in a person's life takes a huge amount of storage, but costs for this service are essentially zero in 2037. Life images are beamed through the air to an archive location using quantum cryptograph unbreakable making such transmissions totally secure.

Meanwhile Alicia enters the home com-center to begin her workday. She began telecommuting back at the turn of the century when her employer the same corporation Randolph works for realized it would increase employee productivity, and help alleviate transportation problems, by reducing work commutes.

Alicia communicates with co-workers and business associates scattered around the globe using holographic virtual reality (HVR), which provides a total "being there" feeling. Handshakes and an occasional pat-on-the-back are actually felt as if everyone were in the same room. As a medical information specialist, Alicia helps develop new world markets for her company.

This morning, she is trying to convince a new South African firm to expand distribution through her company. But just as she begins focusing on the figures, charts, and diagrams on her screen, there's a loud noise from the other room. Alicia runs into the living room to find that Bradley has accidentally backed into the antique side table, sending glass objects and mementos crashing to the floor. Alicia shrieks at the robot this is the third time this week he's done this! Once again, Alicia tells him to gather some nanobots to clean up the mess and make repairs.

Meanwhile on the way to work, Randolph has a problem. A police matter has brought transportation to a halt. About two blocks from the office, a blue-jump-suited robot police officer seemed to appear out of nowhere to stop the dented old auto-drive clunker ahead of him. When the officer fed the driver's biometric eye scan to Las Vegas Central Intelligence, something obviously hadn't measured up.

Within minutes, the police officer electronically "cloaked" the offender and sped away in the emergency electro-lane towing the empty driverless clunker. Later, Randolph learned from a wireless news feed, that the clunker's guidance system was defective. It was removed for safety reasons, because it posed a danger to other cars on the auto-drive roadways. Traffic finally began moving again, and Randolph soon arrived at the company parking facility.

9:00 A.M.

In Genetics 3, Mike and his classmates get a chance to study HVR images of gene combinations at their stations. Led by Ms. Michael, the students observe various combinations of gene engineering to see the changing affects on humans. They prepare for a seminar that Mike and his fellow sixth-graders will attend at a nearby genetic engineering lab. Mike, who thinks he'd rather be a rock star when he grows up, spends the period drawing guitars in his textbook.

Back at the Smith home, Bradley brings Carlotta her cheer leader costume from the replicator and says "you'll look smashing in this, Carlotta; it fits you perfect and has the team's bright purple and gold colors". Carlotta thanked the robot and asked him to schedule a driverless-taxi to pick her up in 30 minutes.

Bored from recent months of retirement, Carlotta is more than pleased with her new genetically-enhanced youthful body. Her energy level has surpassed her wildest expectations. Last week when she met with a career counselor, she considered two choices, to become an entrepreneur and start a new business in the information services field, or pursue an entertainment career beginning with the cheer-leader tryout for Las Vegas' new basketball team. The entertainment field seemed more attractive. She knows competition will be fierce, but confidence oozes through her veins.

Carlotta watched the driverless taxi pull up in from of the house and is surprised to see someone already sitting in the car. "I guess this is no big deal", she says to herself. "Sharing a ride could be fun. Who knows"? I could meet Mr. Right.

9:30 A.M.

On a rooftop shuttle ride to his office, located on the back of the company lot about 200 yards from the parking facility, Randolph observes a strikingly sophisticated skyline.

The advent of Las Vegas' status as a city that not only boasts the world's most advanced hi-tech gaming facilities, but in 2037, includes world-class office complexes which house more than 100 Fortune 500 company headquarters. Las Vegas has earned the reputation of being the most thriving desert city in America. Locals brag about their clean air, distinct weather seasons, and competitive living costs.

Walking through the doors of his plush, airy office a far cry from the cell-like office configuration of old Randolph greets Cara, his human interface manager. Looking up from her station, Cara tells Randolph that he missed his first meeting and the second meeting is about to begin.

Rushing into the com room, Randolph sees his impatient business associates two bankers in their Southeast Asia office appear to be seated at the table facing a theater-quality digital 3-D holographic screen, which illuminates the entire south wall of the office. Everyone is waiting for an announcement from corporate vice president Mark Demianew in London. Apologizing for being late, Randolph quickly directs an action thought to the conference system, and Froehler's holographic image pops into the room as though she were actually there. The four begin an animated discussion about purchasing assets from a bankrupt Thai textile company.

10:00 A.M.

Carlotta cautiously climbs into the taxi where she finds a handsome young man named Terry who says he recently moved from Seattle and lives just one block from the Smith house. Terry's robot had intercepted the taxi's computer as it approached the neighborhood and discovered it was headed for the Desert Stars facility, which is where Terry also wanted to go. Ride sharing was initiated after Carlotta and Terry's robots approved the event.

10:30 A.M.

Meanwhile, Sandy and her classmates find themselves in a simulated reality sci-fi class. They are on a trip aboard the starship Howling Circus, racing through space on a seven-year journey searching for an isolated brown dwarf star three light-years from Earth and, if all goes well, the first meeting with an alien civilization from another universe. "This is so real", Sandy thinks, as excitement begins to swell.

Recently, science created microscope-size nanobots that communicate with the brain, creating simulated realities indistinguishable from the real world. Sandy's school was selected to receive the first state-of-the-art programs, which achieve levels of reality similar to those, portrayed in last century's fictional Star Trek Holodeck. "Its break-time", the teacher interrupts "Computer, end program". Sandy looks around and tells her classmate, Alan Van Cleave, that she really felt like she was traveling through space. "I know what you mean", Alan replied. "I actually became space-sick".

Sandy's school, Las Vegas Nano-Metric High, is the latest educational experiment combining virtual reality with new nanotech-assisted realities. Although direct computer-to-brain uploads are expected to be available soon, most parents prefer nano-metrics which strives for an accurate learning experience achieved more naturally through simulated reality.

11:00 A.M.

Back at the com-center, Alicia discovers she must go to the nearest scramjet port, in Los Angeles, to meet Nicholas Kidman, a company executive arriving by scramjet from Sidney Australia. Scramjets super-combustion ram jets can take off, climb into outer space, and whiz around the Earth in minutes; then drop down to their destination. Scramjets can travel to anywhere on Earth in less than an hour. Kidman's one-hour flight arrives at noon, so Alicia must leave right away.

Alicia climbs into the family's auto-drive sports car, which is dual-equipped to drive on computerized "smart" roads, as well as high-speed "maglev" tracks. She makes the 60-minute 290-mile trip in time to meet Nicholas just as he steps off the scramjet. After the two exchange greetings, they head for Las Vegas to meet Alicia's boss at the facility where Randolph works.

Nicholas tells Alicia, at this important meeting, they hope to find solutions that will offset financial losses the company anticipates from the effects of nanotech replicators. After Nicholas mentions he plans to spend a couple of days in Las Vegas, Alicia invites him to a "home style" dinner at 7:00 P.M. at her house that evening. Nicholas accepts.

11:30 A.M.

At the Desert Stars facility, Carlotta begins practicing routines given her by the executive in charge of entertainers. After finishing, she notices a dark figure in the far corner of the room walking closer, while slowly applauding her performance. She finally sees that it's Terry, who explains he is Saul's father; is 105 years of age, and has also undergone genetic rejuvenative therapy.

Carlotta thinks "Wow I'll bet Bradley knew all along what he was doing. ` Way to go Bradley, you're quite the matchmaker". Terry tells Carlotta her routine was fabulous and he would like to know her better. He suggests a "free-road" trip that evening followed by dinner at the Las Vegas Nightery, a swank new place just off the strip.

Carlotta accepts the invitation and tells him she love "free-roading". Free roads are specially-designated streets and highways for manual driving only. Most auto-drive cars can also be driven manually, and many people especially the adventurous enjoy "putting the pedal to the metal" on occasion. Terry asks if he can pick her up at 5 O'clock and Carlotta says she will be waiting.

12:30 P.M.

After a busy morning, Alicia enters La Caf St Pierre and sees her friend, assistant manager Maria Juarez, at the door. Maria mentions that Randolph emailed that he would be a few minutes late, and suggested you order for him. "If you're willing to be adventurous", Maria says, "I recommend broiled albacore steaks marinated in a Napa Valley port. It's the latest rage".

Alicia tells her that sounds great. Randolph soon arrived, and as usual, lunch was fabulous and filling. Afterwards, they discuss Mike's problems in school. Bradley forwarded an email from Ms Michael saying that Mike was in danger of receiving failing grades. She outlined what will be necessary to turn the situation around.

Sharing a ride back to their offices, they wondered what will ever come of their "gifted" child. They selected neuronal enhancements for Mike at birth. There were no geniuses on either side of their families, and they thought it would be a great idea. But little did they realize that geniuses can experience a myriad of problems adjusting into society.

1:00 P.M.

As Sandy and her friend Alan enter the classroom, M35, an advanced robot teacher tells everyone to please be seated. Today, we will address issues relating to the use of electronic wombs, the teacher explains. Artificial wombs first entered the scene in 2020, and have since become extremely popular.

This controversial technology was originally created as an extensive care system to increase survival of unhealthy embryos. Later, however, these marvels were accepted as a legitimate birthing option for women who simply did not want to experience the discomfort of pregnancy. Advocates and opponents aggressively try to shower the public with their partisan views.

Public education forays into alternate birthing systems are heralded as a brilliant teaching experiment, and Sandy's school was selected as one of the first in the nation to receive the new curriculum. Educators hope that by enlightening parents on new technologies, the overall human experience will be advanced.

Sandy and Alan are impressed. "I know I'm only 15", Alan says, "but with today's science, I believe that soon only perfect children will be created. Technology has come a long way since our parent's day", he says. Sandy agrees, "2037 is the greatest time ever to be a teenager".

2:00 P.M.

Randolph arrives home just as Alicia is ending her workday. Nano-replicators have dramatically lowered living costs, reducing much of the need for income. Most people work about 20 hours or less each week. This gives everyone more time for family, friends, and recreation.

Excited about tonight's dinner with their Australian guest, Randolph and Alicia discuss the details. Social activities like this are becoming more popular and are literally changing the American recreational scene. People interact more with each other in 2037 than ever before in history. And the Smiths love it.

3:00 P.M.

Bradley challenges his master to a video game, but Randolph says no he wants to focus on tonight's dinner activity, and asks Alicia if she could use some help. Alicia assures him she does not need any help, but thanks him for asking. Randolph says "OK Bradley, show me your best"! They decide on Craig's Asteroids 2100, an upgrade of one of the oldest games in existence, and Randolph quickly wins. Bradley wants another chance, but Randolph says no, he needs to take a break.

4:00 P.M.

As Randolph relaxes in the den, he thought-clicks the Internet on. The terabyte-speed world-wide-web places images on all four walls, ceiling, and floor. It can access more than a trillion, trillion pages of information and display any movie or TV show ever produced.

Today, Randolph decides to watch the latest program in his favorite series: Techno Wonder The New Adventures of Nano-Man. Skipping through commercials and boring parts, he begins to wonder what it is he likes about this dumb program. After feeling much too bored, he turns to an international network news program to learn the latest in world happenings.

5:00 P.M.

Terry pulls up in front of the Smith house in his new hybrid auto-manual-drive sports car. "You are so punctual", Carlotta comments, as Bradley invites Terry into the house. "Oh, you shouldn't have", Carlotta says, as she accepts the beautiful yellow roses Terry hands her. The two can hardly conceal their excitement anticipating this first date, and decide to leave Carlotta tells Terry she will introduce him to her family later.

"Free road area 29", Terry voices into the car's computer and off they go. In about 10 minutes, the car computer announces, "entering manual drive road" and the two begin a journey that Carlotta will remember forever.

5:15 P.M.

As Terry heads downhill on a long straight stretch, Carlotta glances at the speedometer "holy cow", she says; "Terry, do you realize we are doing 150"? Terry says "no problem, this baby will do even more if I let it". Suddenly appearing from nowhere, a sports car approaches driving on the wrong side of the road. Before they can even think, Carlotta hears a huge explosion as the two cars crash. An eerie silence covers the area.

5:30 P.M.

It seems an eternity passes before Carlotta's eyes open at Las Vegas General Hospital. The first sight she sees is her family Randolph, Alicia, Sandy, and Mike. "We were all so worried", Alicia said. "For a while, the doctors were not sure the new experimental cell-repair mechanisms would work, but when we saw all your vital facilities returning, we new the machines were successful and we watched your body as it was being rebuilt, cell by cell. It was like magic. We all jumped for joy; we were so thankful. Mom, you gave everyone quite a scare".

Randolph, responding to Carlotta's look of concern, told her that Terry did not make it. His body was so destroyed in the crash, that nanobots could not revive enough cells to begin life-saving procedures. Terry died, Randolph told his mother. As tears swelled in Carlotta's eyes, Alicia told her to not blame herself. "Terry must surely have known what he was doing. For reasons we may never know, this probably happened for a purpose. Only time will tell".

The driver of the other car was also killed in the crash. Officials found both black boxes recording systems similar to those used by airlines, which are installed in all vehicles. A thorough investigation revealed the wrong-way driver was under the influence of a new mind-altering virtual reality virus. The illegal virus gathers pleasant memories from its host and amplifies happy feelings, but sometimes makes the user confused.

"How awful", Carlotta says. "With all our modern science and technologies in 2037, people still get hooked on illegal drugs that cause death". She wonders if this kind of destruction will ever end. Seeing that Carlotta is physically OK and had regained emotional stability, Alicia reminded everyone about their guest coming to dinner at 7 O'clock, and the family headed for home in the hospital's driverless van.

7:00 P.M.

As the replicator cooks dinner pasta, salmon filets, and an assortment of organic vegetables, Bradley unleashes nanobots that quickly create a dining room fit for royalty a handsome oak table with matching padded chairs illuminated under a beautiful 20th century chandelier, and original china dinnerware pieces.

Alicia fears the dinner won't be perfect, but Bradley assures her everything is in order, and it will be a perfect evening. The house security system announces a visitor approaching the front door, and confirms that it is Nicholas. The front door opens and the house audio system delivers a verbal "come in, Mr. Kidman". "Nicholas, I would like you to meet my family", Alicia says, as she introduces her guest.

The dinner was a huge success. Nicholas complimented Alicia on her wonderful food selections, and asked her to email the salmon recipe. After the meal, the smiths entertain in the recreation room by calling up a new state-of-the-art simulation game. Nicholas enjoyed it so much, Alicia decided to replicate a copy and give it to him as a gift.

9:00 P.M.

Sandy asks her parents if she can talk with them about a personal matter. Randolph looks a little uncomfortable, but he agrees. Sandy wants their permission to have some of her eggs frozen for use at a later time should she decide to create a child. After talking about all the responsibilities of being a parent, and how frustrating it can become on occasion, they tell her that she has their permission. Sandy happily thanks them.

11:30 P.M.

As another day finally brings its long-awaited retreat, Alicia and Randolph lie in bed exhausted after the ordeal with Carlotta. They are thankful she is OK and hope she will not be quite so bold in the future. Then they talk about what a fabulous dinner they put on for Nicholas. "He was really impressed", Randolph tells his wife. "You were a great hostess".

Finally, the conversation rolls over to Mike. Should they cut back on his recreation activities until he improves his grades? Alicia's not sure. For now, she just wants to sleep. Groggily, Randolph gives his wife a good night hug and warm kiss, grabs the Smart House remote, and punches a few buttons. House lights begin to dim, outside doors lock, and the security system and fire alarm click on. The Smiths are fast asleep within minutes.

12:00 Midnight

Finished with his duties, Bradley performs a last minute silent double-check on house security, practices a silly, human-like grin, and quietly stores himself into a closet.

This piece, written 04/24/2012 will appear in various print media and blogs; comments welcome. See other articles by Dick at http://www.positivefuturist.com; click the "published work" tab.


#5117 From: "Shawn Jipp" <sjipp@...>
Date: Fri Apr 20, 2012 2:34 pm
Subject: Meeting tonight!
sjipp
Send Email Send Email
 

Hello Futurists of Las Vegas!

Tonight will be our April dinner meeting. Remember that our meetings are always held on the third Friday of each month .

The topic that was voted on by majority vote at last meeting was World War 3. Please come prepared to discuss this topic:

      Do you believe WWIII will occur?

      If so, approximately when and under what conditions would WWIII start?

      If not, why not?

      Is mankind doomed to wars of a global scale?

      Does science help or hinder WWIII from occurring?

      Do politics help or hinder WWIII from occurring?

      Does mankind's fascination with religion help or hinder WWIII from occurring?

      Will mankind's propensity for war doom us from ever leaving earth to colonize other planets?

      Can we personally do anything to help minimize WWIII from occurring?

We will also have show and tell with our affordable 3 dimensional television from LG electronics. We will demonstrate a few minutes of a 3D movie, a few minutes from a Futurama cartoon about the future! (in simulated 3D), and a few minutes of a Star Trek Voyager episode (in simulated 3D.)

Feel free to bring a friend!
See you tonight!

///////Shawn

Here are the directions:

Denny's

3081 South Maryland Parkway, Las Vegas, NV

(702) 734-1295   dennys.com

http://maps.google.com/maps?q=Denny's,+South+Maryland+Parkway,+Las+Vegas,+NV&hl=en&ll=36.134114,-115.132899&spn=0.014471,0.033023&sll=36.147856,-115.140967&sspn=0.028936,0.082397&oq=dennys+maryland+parkway+las+vegas,+nv&hq=Denny's,&hnear=S+Maryland+Pkwy,+Las+Vegas,+Nevada&t=m&fll=36.131983,-115.137405&fspn=0.014471,0.041199&z=16

 


#5118 From: "Shawn Jipp" <sjipp@...>
Date: Fri Apr 20, 2012 2:57 pm
Subject: RE: Meeting tonight!
sjipp
Send Email Send Email
 

We meet at 7PM!

 


#5119 From: Shawn <sjipp@...>
Date: Fri Apr 20, 2012 3:19 pm
Subject: Re: Meeting tonight!
sjipp
Send Email Send Email
 
OK Carl. hope to see you next month. Take care.

///////Shawn
--
Sent from my Samsung Galaxy SII Android phone using K-9 mail.

#5120 From: "Carl K. Long" <slingshotfirst@...>
Date: Fri Apr 20, 2012 3:04 pm
Subject: Re: Meeting tonight!
carlklong
Send Email Send Email
 

Hello All:

Sorry I won't be able to make this meet.  Been having some medical trouble that is about over.

Have a good meeting,

Carl Long

-----Original Message-----
From: Shawn Jipp
Sent: Apr 20, 2012 7:34 AM
To: lvfuturists@yahoogroups.com
Subject: [lvfuturists] Meeting tonight!

 

Hello Futurists of Las Vegas!

Tonight will be our April dinner meeting.  Remember that our meetings are always held on the third Friday of each month .

The topic that was voted on by majority vote at last meeting was World War 3.  Please come prepared to discuss this topic:

·      Do you believe WWIII will occur?

·      If so, approximately when and under what conditions would WWIII start?

·      If not, why not?

·      Is mankind doomed to wars of a global scale?

·      Does science help or hinder WWIII from occurring?

·      Do politics help or hinder WWIII from occurring?

·      Does mankind's fascination with religion help or hinder WWIII from occurring?

·      Will mankind's propensity for war doom us from ever leaving earth to colonize other planets?

·      Can we personally do anything to help minimize WWIII from occurring?

We will also have show and tell with our affordable 3 dimensional television from LG electronics.  We will demonstrate a few minutes of a 3D movie, a few minutes from a Futurama cartoon about …the future! (in simulated 3D), and a few minutes of a Star Trek Voyager episode (in simulated 3D.)

Feel free to bring a friend!
See you tonight!

///////Shawn

Here are the directions:

Denny's

3081 South Maryland Parkway, Las Vegas, NV

(702) 734-1295  · dennys.com

http://maps.google.com/maps?q=Denny's,+South+Maryland+Parkway,+Las+Vegas,+NV&hl=en&ll=36.134114,-115.132899&spn=0.014471,0.033023&sll=36.147856,-115.140967&sspn=0.028936,0.082397&oq=dennys+maryland+parkway+las+vegas,+nv&hq=Denny's,&hnear=S+Maryland+Pkwy,+Las+Vegas,+Nevada&t=m&fll=36.131983,-115.137405&fspn=0.014471,0.041199&z=16


#5121 From: Carol Jean Tillman DVM <caroljean@...>
Date: Sat Apr 21, 2012 7:12 am
Subject: WW III and Upcoming Meeting
caroljean@...
Send Email Send Email
 
Hi Shawn,
Thinking of our next Futurists meeting, on Transportation,
I found this 'alternative' to the wheeled Martian Rover, the 'Tumbleweed'!

http://news.discovery.com/videos/space-tumbleweed-rovers-could-explore-mars.html

A different form of transportation on Mars!

You left off the last two questions tonight:
Will mankind's propensity for war doom us from ever leaving earth to colonize other planets?
   
Maybe. In my opinion, as mankind needs to be more 'far sighted' to see that in order to survive as a species, if we deplete Earth, we need to colonize other planets. If we wear blinders, only looking to wage war on our neighbors, humans will NEVER get off the planet.


 Can we personally do anything to help minimize WWIII from occurring?

YES! Practice ZERO POPULATION GROWTH and support EDUCATION! And maybe vote for a woman President!

Live long and Prosper,
Carol Jean





Hello Futurists of Las Vegas!
Tonight will be our April dinner meeting.  Remember that our meetings are always held on the third Friday of each month .
The topic that was voted on by majority vote at last meeting was World War 3.  Please come prepared to discuss this topic:
      Do you believe WWIII will occur?
      If so, approximately when and under what conditions would WWIII start?
      If not, why not?
      Is mankind doomed to wars of a global scale?
      Does science help or hinder WWIII from occurring?
      Do politics help or hinder WWIII from occurring?
      Does mankind's fascination with religion help or hinder WWIII from occurring?
      Will mankind's propensity for war doom us from ever leaving earth to colonize other planets?
      Can we personally do anything to help minimize WWIII from occurring?
We will also have show and tell with our affordable 3 dimensional television from LG electronics.  We will demonstrate a few minutes of a 3D movie, a few minutes from a Futurama cartoon about the future! (in simulated 3D), and a few minutes of a Star Trek Voyager episode (in simulated 3D.)
Feel free to bring a friend!
See you tonight!
///////Shawn
Here are the directions:
Denny's
3081 South Maryland Parkway, Las Vegas, NV
(702) 734-1295   dennys.com
http://maps.google.com/maps?q=Denny's,+South+Maryland+Parkway,+Las+Vegas,+NV&hl=en&ll=36.134114,-115.132899&spn=0.014471,0.033023&sll=36.147856,-115.140967&sspn=0.028936,0.082397&oq=dennys+maryland+parkway+las+vegas,+nv&hq=Denny's,&hnear=S+Maryland+Pkwy,+Las+Vegas,+Nevada&t=m&fll=36.131983,-115.137405&fspn=0.014471,0.041199&z=16
 


#5122 From: Eric Anderson <eric25001@...>
Date: Tue Apr 24, 2012 2:49 am
Subject: Medicinal applications of fullerenes
eric25001
Send Email Send Email
 
As a follow up to a previous post on a 2 fold increase in lifespans of rats feed C60 ==>
 
Below is the abstract and a link to a 2007 article on Buckyballs aka fullerenes.  This article reviews several articles that provide a more widespread understanding of how carbon 60 might play a very important role in medicine.  Also more it has links to more recent research.  
 
One can imagine much longer and healthier life spans and much lower per year medical costs.  I would think one could use a metabolite profile of older animals with and without C60 diets.  Then if C60 proves to have the health and lifespan increases in animals a human trial with metabolite profiles could be done.  Eric from the SALT pits.
 
Live long and prosper!
 
Medicinal applications of fullerenes
 
 
Fullerenes have attracted considerable attention in different fields of science since their discovery in 1985. Investigations of physical, chemical and biological properties of fullerenes have yielded promising information. It is inferred that size, hydrophobicity, three-dimensionality and electronic configurations make them an appealing subject in medicinal chemistry. Their unique carbon cage structure coupled with immense scope for derivatization make them a potential therapeutic agent. The study of biological applications has attracted increasing attention despite the low solubility of carbon spheres in physiological media.
The fullerene family, and especially C60, has appealing photo, electrochemical and physical properties, which can be exploited in various medical fields. Fullerene is able to fit inside the hydrophobic cavity of HIV proteases, inhibiting the access of substrates to the catalytic site of enzyme. It can be used as radical scavenger and antioxidant. At the same time, if exposed to light, fullerene can produce singlet oxygen in high quantum yields. This action, together with direct electron transfer from excited state of fullerene and DNA bases, can be used to cleave DNA. In addition, fullerenes have been used as a carrier for gene and drug delivery systems. Also they are used for serum protein profiling as MELDI material for biomarker discovery. In this review we report the aspects of medicinal applications of fullerenes.
 
Click link for the article.

#5123 From: "joealwine" <joealwine@...>
Date: Tue Apr 24, 2012 4:08 am
Subject: Nano No Nos
joealwine
Send Email Send Email
 
#5124 From: goldconsul@...
Date: Tue Apr 24, 2012 5:21 am
Subject: Re: Medicinal applications of fullerenes
goldconsul@...
Send Email Send Email
 
Thanks Eric.  That is a good and useful article about an interesting class of compounds. I agree studying them could  be advantageous.
 
Walter
 
In a message dated 4/23/2012 7:50:07 P.M. Pacific Daylight Time, eric25001@... writes:
 

As a follow up to a previous post on a 2 fold increase in lifespans of rats feed C60 ==>
 
Below is the abstract and a link to a 2007 article on Buckyballs aka fullerenes.  This article reviews several articles that provide a more widespread understanding of how carbon 60 might play a very important role in medicine.  Also more it has links to more recent research.  
 
One can imagine much longer and healthier life spans and much lower per year medical costs.  I would think one could use a metabolite profile of older animals with and without C60 diets.  Then if C60 proves to have the health and lifespan increases in animals a human trial with metabolite profiles could be done.  Eric from the SALT pits.
 
Live long and prosper!
 
Medicinal applications of fullerenes
 
 
Fullerenes have attracted considerable attention in different fields of science since their discovery in 1985. Investigations of physical, chemical and biological properties of fullerenes have yielded promising information. It is inferred that size, hydrophobicity, three-dimensionality and electronic configurations make them an appealing subject in medicinal chemistry. Their unique carbon cage structure coupled with immense scope for derivatization make them a potential therapeutic agent. The study of biological applications has attracted increasing attention despite the low solubility of carbon spheres in physiological media.
The fullerene family, and especially C60, has appealing photo, electrochemical and physical properties, which can be exploited in various medical fields. Fullerene is able to fit inside the hydrophobic cavity of HIV proteases, inhibiting the access of substrates to the catalytic site of enzyme. It can be used as radical scavenger and antioxidant. At the same time, if exposed to light, fullerene can produce singlet oxygen in high quantum yields. This action, together with direct electron transfer from excited state of fullerene and DNA bases, can be used to cleave DNA. In addition, fullerenes have been used as a carrier for gene and drug delivery systems. Also they are used for serum protein profiling as MELDI material for biomarker discovery. In this review we report the aspects of medicinal applications of fullerenes.
 
Click link for the article.


#5125 From: Shawn Jipp <sjipp@...>
Date: Tue Apr 24, 2012 5:46 am
Subject: Re: Nano No Nos
sjipp
Send Email Send Email
 
Thanks Joe for these great links!  As responsible Futurists, we must admit that mankind cannot just go forward blindly creating things that may threaten our very existence.  We must be responsible.  We must be concerned.  Assuming that everything will work out just fine is irresponsible.

///////Shawn

Sent from my iPad

On Apr 23, 2012, at 9:08 PM, "joealwine" <joealwine@...> wrote:


#5126 From: "Shawn Jipp" <sjipp@...>
Date: Wed Apr 25, 2012 4:54 am
Subject: The Scale of Things
sjipp
Send Email Send Email
 

I find this to be awe inspiring, humbling, and deeply profound!

 

http://htwins.net/scale2/scale2.swf?bordercolor=white

 


#5127 From: "joealwine@..." <joealwine@...>
Date: Tue Apr 24, 2012 4:12 pm
Subject: super-weeds
joealwine
Send Email Send Email
 
More trouble for the bees!

   http://www.cnbc.com/id/47153938

____________________________________________________________
53 Year Old Mom Looks 33
The Stunning Results of Her Wrinkle Trick Has Botox Doctors Worried
http://thirdpartyoffers.juno.com/TGL3141/4f96d1389045ba797aest05duc

#5128 From: "joealwine@..." <joealwine@...>
Date: Wed Apr 25, 2012 6:00 pm
Subject: corn and bees
joealwine
Send Email Send Email
 
Just a few links from Google search on corn and bees.

http://www.tomorrowsworld.org/commentary/more-corn-fewer-bees

http://www.csmonitor.com/Science/2012/0406/Is-corn-syrup-killing-the-honeybees-v\
ideo

http://www.care2.com/greenliving/bee-killing-pesticide-could-be-banned.html

____________________________________________________________
53 Year Old Mom Looks 33
The Stunning Results of Her Wrinkle Trick Has Botox Doctors Worried
http://thirdpartyoffers.juno.com/TGL3141/4f983beeed2b5b2bcb5st04duc

#5129 From: David M Gordon <gordondm@...>
Date: Fri Apr 27, 2012 12:51 am
Subject: Is the Heyday of Carbon Nanotubes Just Around the Corner?
gordondm
Send Email Send Email
 
The article below is from an investment newsletter. Despite that provenance, the essay is both fascinating and of interest to this group.
David M Gordon

Is the Heyday of Carbon Nanotubes Just Around the Corner?
A few weeks ago in these pages we ran an article in which we touched on one particular technology that I'd like to delve into more deeply today. Carbon nanotubes (CNTs) warrant additional discussion partly because of the sheer scope of their potential applications and partly because of recent breakthroughs that are bringing their heyday closer to reality.
Although the term "carbon nanotubes" still sounds rather futuristic, scientists have known about their existence for quite some time. Sumio Iijima is typically credited with discovering CNTs by accident in 1991, but a careful reading of the literature actually shows that Russian scientist LV Radushkevich and his collaborators reported on CNTs as early as 1952. Then, in the mid-1970s, a collaborative effort between scientists from Japan and France reported the observation of CNTs via electron microscopy. The actual discovery of CNTs came with little fanfare, however, since nobody at the time thought they could be fabricated in meaningful amounts.
Fast forward about 15 years, to when Huffman in the US and Kratschmer in Germany developed the arc evaporation method to produce macroscopic amounts of C60, a carbon molecule in the shape of a soccer ball; these are often referred to now as "buckyballs." Iijima - who was studying the surfaces of the electrodes used in the arc evaporation process - found large amounts of multi-wall carbon nanotubes (MWCNTs) mixed with other graphite particles. The ability to source MWCNTs was of great importance... but there was more to come.
In early 1993, both Iijima (working at NEC in Japan) and Donald Bethune (of IBM) independently isolated single-wall carbon nanotubes (SWCNTs). MWCNTs are easier to produce in high volume quantities than SWCNTs, but they're less sought after because their structural imperfections tend to diminish their desirable material properties. SWCNTs are more pliable than MWCNTs, and they have unique electronic and mechanical properties which are widely useful. Thus, for the purposes of this article, when we discuss CNTs we'll mostly be referring to SWCNTs.
CNTs are an allotrope of carbon that can be thought of as a sheet of graphene (a hexagonal lattice of carbon) rolled into a seamless cylinder. They are highly flexible and very strong (100 times stronger than steel at one-sixth the weight). They also have high electrical conductivity (as high as copper) and high thermal conductivity (as high as diamond). And they can easily penetrate membranes such as cell walls - in effect acting like a needle at the cellular level.
Due to the incredible properties of CNTs, research labs and companies the world over have been promising technological breakthroughs - in fields ranging from electronics and medicine to construction and aerospace - for the past two decades.
Some of these include:
  • Building transistors from CNTs to enable minimum transistor dimensions of a few nanometers, and developing techniques to manufacture integrated circuits built with nanotube transistors.
  • Creating drug-delivery systems with CNTs. One idea is to fill the tubes with a mixture of drugs and water molecules, then heat up the tubes with an infrared laser to boil the water inside, and once they've reached the desired target in the body, blow them up to release the drugs; i.e., "drug grenades" if you will.
  • Constructing superstrong, lightweight bridges and buildings out of CNTs instead of steel.
  • Replacing silicon with a thin layer of CNTs in window-based solar-energy production for a transparent solar window.
It's true that a few applications of CNTs are commercialized today (some products containing CNTs include paint, vehicle parts, and sports equipment), but these represent bulk applications in which MWCNTs play an auxiliary role to reinforce mechanical, thermal, or electric properties. The technological revolution in products that capitalize on the unique mechanical and electric properties of SWCNTs has been slower to materialize.
The main reason that the most promising applications have not yet come to pass is the lack of reproducibility of quality CNTs. Simply by changing the bonding configuration with itself, carbon can form a large variety of isomers from the same number of atoms. And the number of these isomers increases almost exponentially with the number of carbon atoms. For example, C60 has one isomer, while C120 has about 14,000. According to Dr. Gyula Eres, from the Materials Science and Technology Division of Oak Ridge National Laboratory, "The large number of isomers leads to a non-uniform product distribution that can dramatically change in response to relatively small changes in experimental parameters that are often difficult or impossible to account for. This is why the various methods used for synthesis of CNTs produce such vastly different distributions of single wall and multi-wall CNTs along with other carbon structures that are undesirable side products of the synthesis process."
But the long-awaited CNT revolution may be just around the corner, thanks to a couple of recent improvements to the production process.
Since the early '90s, CNTs have been described as "rolled-up sheets of graphene," except they couldn't actually be made that way. Instead, they were coaxed into self-assembling using the three typical production techniques of arc discharge, laser ablation, and chemical vapor deposition. It was recently reported, however, that researchers from Harvard and the NanoScience Center of the University of Jyvaskyla in Finland have discovered a new way to make CNTs by means of twisting graphene nanoribbons. The basic idea is easily explained: simply twist the ends of a strap on a backpack and you'll understand what's going on. The new method also supposedly allows for stricter experimental control, which would permit scientists selectively to create various types of CNTs.
Just two weeks ago, another - perhaps even more important - breakthrough in the production of CNTs was announced by a group of researchers from Malaysia. The group claims to have successfully created a method of continuously producing high-quality, pure CNTs at a cost of just $15 to $35 per gram, well below current production costs of $100 to $700 per gram. According to the team, "the system is capable of producing up to 1,000 grams of carbon nanotubes a day." It should be noted that details about this new method are hard to come by, and the group's claim is difficult to substantiate. If it is true, however, it represents a giant step forward in CNT research.
In addition to novel production techniques, we've also recently seen advances in the application of CNTs in electronics. It's been common knowledge for years that scaling bulk silicon transistors will be extremely difficult (if not impossible) once we get down to about 15 nm. Intel's new chips, coming out later this week, employ the company's Ivy Bridge 22 nm technology. Thus, we've almost reached the theoretical limit of being able to scale down planar transistors. (Intel's new chips do incorporate 3D transistor technology, but that's a discussion for another day.) One possible solution to this problem is to swap silicon transistors for ones made with CNTs. The problem is that nobody knew whether CNT transistors could offer performance advantages over silicon at sub-10 nm lengths - until now.
Dr. Aaron Franklin and his team at IBM recently showed that CNTs can operate as excellent switches at molecular dimensions of only 9 nm; i.e., less than half the size of the leading silicon technology. And these transistors deliver more current and require less operating power than silicon-based ones of similar size. This is the first experiment to clearly demonstrate that silicon can be replaced with CNTs in future semiconductor technology, and the results propel such devices to the forefront of future microchip technologies.
These recent developments add to our already bullish outlook for the future prospects of CNTs. But it's important to keep in mind that like any technology, it doesn't come without risks. Some studies have shown that CNTs, especially longer ones, can pose health risks similar to asbestos' if inhaled. Other studies have shown that CNT inhalation can also suppress the immune system. Thus, their ultimate use in industry could be significantly curbed by regulation.
Nevertheless, CNTs represent a disruptive technology the likes of which comes along once every few generations (if that). We're convinced that it is poised to reshape industries, create new ones, and make savvy investors very wealthy in the process.  <snip>



#5130 From: Eric Anderson <eric25001@...>
Date: Fri Apr 27, 2012 1:09 am
Subject: Re: Is the Heyday of Carbon Nanotubes Just Around the Corner?
eric25001
Send Email Send Email
 
David and all
 
I still think the two fold lifespan increase in rats is hopeful.
 
If C60 can increase human life to an average of 150 to 200 years it will have a most profound economic impact!  Eric

--- On Thu, 4/26/12, David M Gordon <gordondm@...> wrote:

From: David M Gordon <gordondm@...>
Subject: [lvfuturists] Is the Heyday of Carbon Nanotubes Just Around the Corner?
To: "Las Vegas Future Salon" <lvfuturists@yahoogroups.com>
Date: Thursday, April 26, 2012, 5:51 PM

 
The article below is from an investment newsletter. Despite that provenance, the essay is both fascinating and of interest to this group.
David M Gordon

Is the Heyday of Carbon Nanotubes Just Around the Corner?
A few weeks ago in these pages we ran an article in which we touched on one particular technology that I'd like to delve into more deeply today. Carbon nanotubes (CNTs) warrant additional discussion partly because of the sheer scope of their potential applications and partly because of recent breakthroughs that are bringing their heyday closer to reality.
Although the term "carbon nanotubes" still sounds rather futuristic, scientists have known about their existence for quite some time. Sumio Iijima is typically credited with discovering CNTs by accident in 1991, but a careful reading of the literature actually shows that Russian scientist LV Radushkevich and his collaborators reported on CNTs as early as 1952. Then, in the mid-1970s, a collaborative effort between scientists from Japan and France reported the observation of CNTs via electron microscopy. The actual discovery of CNTs came with little fanfare, however, since nobody at the time thought they could be fabricated in meaningful amounts.
Fast forward about 15 years, to when Huffman in the US and Kratschmer in Germany developed the arc evaporation method to produce macroscopic amounts of C60, a carbon molecule in the shape of a soccer ball; these are often referred to now as "buckyballs." Iijima - who was studying the surfaces of the electrodes used in the arc evaporation process - found large amounts of multi-wall carbon nanotubes (MWCNTs) mixed with other graphite particles. The ability to source MWCNTs was of great importance... but there was more to come.
In early 1993, both Iijima (working at NEC in Japan) and Donald Bethune (of IBM) independently isolated single-wall carbon nanotubes (SWCNTs). MWCNTs are easier to produce in high volume quantities than SWCNTs, but they're less sought after because their structural imperfections tend to diminish their desirable material properties. SWCNTs are more pliable than MWCNTs, and they have unique electronic and mechanical properties which are widely useful. Thus, for the purposes of this article, when we discuss CNTs we'll mostly be referring to SWCNTs.
CNTs are an allotrope of carbon that can be thought of as a sheet of graphene (a hexagonal lattice of carbon) rolled into a seamless cylinder. They are highly flexible and very strong (100 times stronger than steel at one-sixth the weight). They also have high electrical conductivity (as high as copper) and high thermal conductivity (as high as diamond). And they can easily penetrate membranes such as cell walls - in effect acting like a needle at the cellular level.
Due to the incredible properties of CNTs, research labs and companies the world over have been promising technological breakthroughs - in fields ranging from electronics and medicine to construction and aerospace - for the past two decades.
Some of these include:
  • Building transistors from CNTs to enable minimum transistor dimensions of a few nanometers, and developing techniques to manufacture integrated circuits built with nanotube transistors.
  • Creating drug-delivery systems with CNTs. One idea is to fill the tubes with a mixture of drugs and water molecules, then heat up the tubes with an infrared laser to boil the water inside, and once they've reached the desired target in the body, blow them up to release the drugs; i.e., "drug grenades" if you will.
  • Constructing superstrong, lightweight bridges and buildings out of CNTs instead of steel.
  • Replacing silicon with a thin layer of CNTs in window-based solar-energy production for a transparent solar window.
It's true that a few applications of CNTs are commercialized today (some products containing CNTs include paint, vehicle parts, and sports equipment), but these represent bulk applications in which MWCNTs play an auxiliary role to reinforce mechanical, thermal, or electric properties. The technological revolution in products that capitalize on the unique mechanical and electric properties of SWCNTs has been slower to materialize.
The main reason that the most promising applications have not yet come to pass is the lack of reproducibility of quality CNTs. Simply by changing the bonding configuration with itself, carbon can form a large variety of isomers from the same number of atoms. And the number of these isomers increases almost exponentially with the number of carbon atoms. For example, C60 has one isomer, while C120 has about 14,000. According to Dr. Gyula Eres, from the Materials Science and Technology Division of Oak Ridge National Laboratory, "The large number of isomers leads to a non-uniform product distribution that can dramatically change in response to relatively small changes in experimental parameters that are often difficult or impossible to account for. This is why the various methods used for synthesis of CNTs produce such vastly different distributions of single wall and multi-wall CNTs along with other carbon structures that are undesirable side products of the synthesis process."
But the long-awaited CNT revolution may be just around the corner, thanks to a couple of recent improvements to the production process.
Since the early '90s, CNTs have been described as "rolled-up sheets of graphene," except they couldn't actually be made that way. Instead, they were coaxed into self-assembling using the three typical production techniques of arc discharge, laser ablation, and chemical vapor deposition. It was recently reported, however, that researchers from Harvard and the NanoScience Center of the University of Jyvaskyla in Finland have discovered a new way to make CNTs by means of twisting graphene nanoribbons. The basic idea is easily explained: simply twist the ends of a strap on a backpack and you'll understand what's going on. The new method also supposedly allows for stricter experimental control, which would permit scientists selectively to create various types of CNTs.
Just two weeks ago, another - perhaps even more important - breakthrough in the production of CNTs was announced by a group of researchers from Malaysia. The group claims to have successfully created a method of continuously producing high-quality, pure CNTs at a cost of just $15 to $35 per gram, well below current production costs of $100 to $700 per gram. According to the team, "the system is capable of producing up to 1,000 grams of carbon nanotubes a day." It should be noted that details about this new method are hard to come by, and the group's claim is difficult to substantiate. If it is true, however, it represents a giant step forward in CNT research.
In addition to novel production techniques, we've also recently seen advances in the application of CNTs in electronics. It's been common knowledge for years that scaling bulk silicon transistors will be extremely difficult (if not impossible) once we get down to about 15 nm. Intel's new chips, coming out later this week, employ the company's Ivy Bridge 22 nm technology. Thus, we've almost reached the theoretical limit of being able to scale down planar transistors. (Intel's new chips do incorporate 3D transistor technology, but that's a discussion for another day.) One possible solution to this problem is to swap silicon transistors for ones made with CNTs. The problem is that nobody knew whether CNT transistors could offer performance advantages over silicon at sub-10 nm lengths - until now.
Dr. Aaron Franklin and his team at IBM recently showed that CNTs can operate as excellent switches at molecular dimensions of only 9 nm; i.e., less than half the size of the leading silicon technology. And these transistors deliver more current and require less operating power than silicon-based ones of similar size. This is the first experiment to clearly demonstrate that silicon can be replaced with CNTs in future semiconductor technology, and the results propel such devices to the forefront of future microchip technologies.
These recent developments add to our already bullish outlook for the future prospects of CNTs. But it's important to keep in mind that like any technology, it doesn't come without risks. Some studies have shown that CNTs, especially longer ones, can pose health risks similar to asbestos' if inhaled. Other studies have shown that CNT inhalation can also suppress the immune system. Thus, their ultimate use in industry could be significantly curbed by regulation.
Nevertheless, CNTs represent a disruptive technology the likes of which comes along once every few generations (if that). We're convinced that it is poised to reshape industries, create new ones, and make savvy investors very wealthy in the process.  <snip>



#5131 From: Eric Anderson <eric25001@...>
Date: Tue May 1, 2012 5:07 am
Subject: Synthetic stool a prospective treatment for C. difficile
eric25001
Send Email Send Email
 
Gut Bacteria! Many diseases might be helped with this approach.  Also research into the gut bacteria might show lifespan increases and illness reduction with given bacteria ratios and or types.  Eric from the SALT pits
 

Synthetic stool a prospective treatment for C. difficile

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile)

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C. difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.
"A synthetic stool transplant has a lot of potential because we can control what goes in and we can alter, change, or modify it as necessary," says Elaine Petrof, an assistant professor in the Department of Medicine at Queen's University and in the Gastrointestinal Disease Research Unit (GIDRU) at Kingston General Hospital.
Dr. Petrof and her collaborator at the University of Guelph, Emma Allen-Vercoe, believe that a stool compound made from synthetic or "purified" bacteria could significantly improve on regular stool transplants. It could eliminate the chance of transmitting an infectious disease through fecal bacteria; physicians could tailor the mixture so as to increase patient acceptance; it would be easily reproducible; and, it may appeal to both doctors and patients as a 'cleaner' therapy.
Dr. Petrof and Dr. Allen Vercoe, an anaerobic microbiologist specializing in intestinal bacteria, are working closely to develop such a therapy. The goal behind their synthetic stool project is to offer a single-dose remedy, putting an end to revolving-door hospital visits for patients with recurring symptoms. Currently, they are continuing their research before using it as a new therapy.
###
Dr. Petrof recently presented the project's preliminary findings at the Beneficial Microbes Conference in Noordwijkerhout, the Netherlands.

#5132 From: Shawn Jipp <sjipp@...>
Date: Tue May 1, 2012 8:17 am
Subject: Great Photo News In Our Future!
sjipp
Send Email Send Email
 
#5133 From: "joealwine@..." <joealwine@...>
Date: Tue May 1, 2012 4:59 pm
Subject: Nanobots
joealwine
Send Email Send Email
 
http://www.smartplanet.com/blog/savvy-scientist/tomorrows-nanobots-today/441?tag\
=nl.e660

____________________________________________________________
53 Year Old Mom Looks 33
The Stunning Results of Her Wrinkle Trick Has Botox Doctors Worried
http://thirdpartyoffers.juno.com/TGL3141/4fa016782a10be73475st06duc

#5134 From: "Shawn Jipp" <sjipp@...>
Date: Tue May 1, 2012 8:31 pm
Subject: Battery Charging of the Future?
sjipp
Send Email Send Email
 
#5135 From: "Shawn Jipp" <sjipp@...>
Date: Wed May 2, 2012 2:06 pm
Subject: Terahertz microchip could let cell phones see through walls
sjipp
Send Email Send Email
 

Richardson, TX--Researchers at UT Dallas have designed a THz microchip that could turn mobile phones into devices that see through opaque objects.


To access this article, go to:

http://www.laserfocusworld.com/articles/2012/04/thz-microchip-ut-dallas.html


#5136 From: Eric Anderson <eric25001@...>
Date: Thu May 3, 2012 5:50 pm
Subject: Double the lifespan C60 followup
eric25001
Send Email Send Email
 
Below is a link to an article with more details about C60 and the increase in lifespan.
 
This requires more study.
Other animal models
Started later in the life cycle
Optimal dose and timeing
 
BUT a two fold increase is attractive
ALSO it appears almost all animals had great benifit
 
Eric from the SALT pits
Comments?
 
 
Countless studies showed that [60]fullerene (C60) and derivatives could have many potential biomedical applications. However, while several independent research groups showed that C60 has no acute or subacute toxicity in various experimental models, more than 25 years after its discovery the in vivo fate and the chronic effects of this fullerene remain unknown. If the potential of C60 and derivatives in the biomedical field have to be fulfilled these issues must be addressed. Here we show that oral administration of C60 dissolved in olive oil (0.8 mg/ml) at reiterated doses (1.7 mg/kg of body weight) to rats not only does not entail chronic toxicity but it almost doubles their lifespan. The effects of C60-olive oil solutions in an experimental model of CCl4 intoxication in rat strongly suggest that the effect on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress. Pharmacokinetic studies show that dissolved C60 is absorbed by the gastro-intestinal tract and eliminated in a few tens of hours. These results of importance in the fields of medicine and toxicology should open the way for the many possible -and waited for- biomedical applications of C60 including cancer therapy, neurodegenerative disorders, and ageing.

The study involved about 60 rats. Six sets of ten rat groups. The weight of the treated rats did not go down so it would suggest they did not severely calorie restrict the rats, although there could have been some intermittent fasting.


 



 

 
The results of this pharmacokinetic study show for the first time that C60 is absorbed by the gastro-intestinal tract. In the case of oily solutions, the drug release rate is controlled by the partition coefficient of the drug between the oily vehicle and the tissue fluid and lipophilic drugs may be released concurrently with the disappearance of the oily vehicle from the injection site.

Four possible mechanisms for C60-liver protection were proposed:
(1) C60 can scavenge large numbers of free radicals
(2) it can act as a decomposition catalyst for O2/H2O2, as it has been postulated for its tris-malonic acid derivatives
(3) as a cytochrome P450 inhibitor as it has been reported for some fullerene derivatives
(4) it can inactivate Kupffer cells (liver resident macrophages) through accumulation and overloading with a large number of C60 aggregates

Pathological examinations show that even at very low doses, 500 times lower than that used previously, C60-olive oil solutions effectively protects the livers against CCl4 toxicity. These results are in agreement with those reported for very low doses of water solution of hydrated C60 fullerene in other experimental models.

The effect of pristine C60 on lifespan emphasizes the absence of chronic toxicity. These results obtained with a small sample of animals with an exploratory protocol ask for a more extensive studies to optimize the intestinal absorption of C60 as well as the different parameters of the administration protocol: dose, posology and treatment duration. In the present case, the treatment was stopped when a control rat died at M17, which proves that the effects of the C60 treatment are long-lasting as the estimated median lifespan for C60-treated rats is 42 months. It can be thought that a longer treatment could have generated even longer lifespans. Anyway, this work should open the road towards the development of the considerable potential of C60 in the biomedical field, including cancer therapy, neurodegenerative disorders and ageing. Furthermore, in the field of ageing, as C60 can be administered orally and as it is now produced in tons, it is no longer necessary to resort to its water-soluble derivatives, which are difficult to purify and in contrast to pristine C60 may be toxic.

 

#5137 From: "gildacabral" <gcabral@...>
Date: Sat May 5, 2012 12:26 am
Subject: Exercise Pill
gildacabral
Send Email Send Email
 

BIOMEDICINE

Discovery Could Lead to an Exercise Pill

A newly identified hormone acts like a workout, and transforms bad fat into good.WEDNESDAY, JANUARY 11, 2012

  • BY KAREN WEINTRAUB
photo

Technology ReviewResearchers have discovered a natural hormone that acts like exercise on muscle tissueburning calories, improving insulin processing, and perhaps boosting strength. The scientists hope it could eventually be used as a treatment for obesity, diabetes, and, potentially, neuromuscular diseases like muscular dystrophy.

In a paper published online today by the journal Nature, the scientists, led by Bruce Spiegelman at the Dana-Farber Cancer Institute in Boston, showed that the hormone occurs naturally in both mice and humans. It pushes cells to transform from white fatglobules that serve as reservoirs for excess caloriesinto brown fat, which generates heat.

Because the hormone is present in both mice and humans, Spiegelman speculates that it may have served as an evolutionary defense against cold by triggering shivering. He named it irisin, after the Greek messenger goddess Iris, who allowed humans to communicate with the gods in Greek mythology, because exercise appears to "talk" to various tissues in the body via irisin.

Mice given irisin lost a few grams in the first 10 days after treatment, the study shows, and certain genes involved in powering the cell were turned on. Irisin also appeared to reduce the damage done by a high-fat diet, protecting mice against diet-induced obesity and diabetes, according to the paper, whose first author is postdoctoral fellow Pontus Bostrm.

"We are hopeful, though we have no evidence, that this hormone may embody some of the other benefits of exercise, perhaps in the neuromuscular system," Spiegelman says. If so, it could also be used to treat disorders like muscular dystrophy and muscle wasting.

Researchers still have to figure out how much benefit irisin could provide someone with diabetes or other health problems, says Spiegelman, also a professor of cell biology and medicine at Harvard Medical School. "I'm optimistic," he says. "I just don't want to overpromise and underdeliver."

Harvard Medical School's Dean Jeffrey Flier, an endocrinologist, says he is quite enthusiastic about the new hormone. The study, he says, "opens up a completely new approach to understanding the links between exercise, body weight, and diabetes."

Flier believes irisin offers strong therapeutic potential. "Though much remains to be learned about the action of irisin, and its status in humans with various diseases, this work has the potential to be a game-changer in the field of metabolic disease."

Last month, Spiegelman formed a Boston-based company named Ember Therapeutics to develop his brown-fat research projects, including irisin. The company raised $34 million in series A financing, and is backed by Third Rock Ventures of Boston.

Harvey Lodish, a professor of biology and bioengineering at MIT, and a member of the Whitehead Institute for Biomedical Research, says it may be harder to make irisin into a drug than Spiegelman anticipates. Lodish tried for years to make adiponectin, a hormone he discovered in the mid-1990s, into a similar drug, but never succeeded.

The concentration of both hormones in the blood is already so high that manufacturing enough to make a difference in health is quite challenging, he says. Maybe irisin will be easier to produce, he says, or maybe it could be delivered via gene therapy, in a modified version of the delivery system Spiegelman used in his researchbut Lodish is dubious.

However, of Spiegelman's new research, he says, "It's very nice, it's very elegant." 


#5138 From: "Shawn Jipp" <sjipp@...>
Date: Sat May 5, 2012 4:02 pm
Subject: My Telescope Camera in 10 years? Maybe
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#5139 From: Shawn Jipp <sjipp@...>
Date: Mon May 7, 2012 4:21 pm
Subject: Free Tickets
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Greetings:

I have a handful of free tickets to the LIGHTFAIR INTERNATIONAL trade show
exhibitions which are happening this Wed-Fri at the LV Convention Center.  If
interested, please send me a private email.  First come, first served and I need
to know today.

Here is information:

http://www.lightfair.com/lightfair/V40/

///////Shawn

Sent from my iPad

#5140 From: Eric Anderson <eric25001@...>
Date: Fri May 11, 2012 6:02 pm
Subject: Free-floating planets in the Milky Way outnumber stars by factors of thousands
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If this is proven it may provide a way to skip accross the Milky Way.  Humans could send robots who could collect resources and work on these exoplanets maybe helping with laser power or fuels for ships from earth to other stars.  Eric from the SALT pits
 

Free-floating planets in the Milky Way outnumber stars by factors of thousands

Researchers say life-bearing planets may exist in vast numbers in the space between stars in the Milky Way

10509_203x153
A few hundred thousand billion free-floating life-bearing Earth-sized planets may exist in the space between stars in the Milky Way. So argues an international team of scientists led by Professor Chandra Wickramasinghe, Director of the Buckingham Centre for Astrobiology at the University of Buckingham, UK. Their findings are published online in the Springer journal Astrophysics and Space Science.
The scientists have proposed that these life-bearing planets originated in the early Universe within a few million years of the Big Bang, and that they make up most of the so-called “missing mass” of galaxies. The scientists calculate that such a planetary body would cross the inner solar system every 25 million years on the average and during each transit, zodiacal dust, including a component of the solar system’s living cells, becomes implanted at its surface. The free-floating planets would then have the added property of mixing the products of local biological evolution on a galaxy-wide scale.
Since 1995, when the first extrasolar planet was reported, interest in searching for planets has reached a feverish pitch. The 750 or so detections of exoplanets are all of planets orbiting stars, and very few, if any, have been deemed potential candidates for life. The possibility of a much larger number of planets was first suggested in earlier studies where the effects of gravitational lensing of distant quasars by intervening planet-sized bodies were measured. Recently several groups of investigators have suggested that a few billion such objects could exist in the galaxy. Wickramasinghe and team have increased this grand total of planets to a few hundred thousand billion (a few thousand for every Milky Way star) - each one harbouring the legacy of cosmic primordial life.
Reference:
Wickramasinghe NC et al (2012). Life-bearing primordial planets in the solar vicinity. Astrophysics and Space Science; DOI 10.1007/s10509-012-1092-8

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